The Botulinum Toxin: from poison to treatment by MH Marion

Botulinum Toxin is a neurotoxin produced by Clostridium Botuli, responsible of Botulism. It’s Alan Scott, a Californian ophthalmologist who had the first the genius idea to use it for the treatment of strabismus (cross eyes) in infant, as an alternative to surgery. He saw very quickly the potential of the Botulinum toxin for the treatment [...]

January 17th, 2017|Blog|Comments Off on The Botulinum Toxin: from poison to treatment by MH Marion

The discovery of the molecular mechanism of the neuroparalytic action of tetanus and botulinum neurotoxins

The discovery of the molecular mechanism of the neuroparalytic action of tetanus and botulinum neurotoxins by Cesare Montecucco My scientific interest in presynaptic neurotoxins begun during a semi-sabbatical at the Institut Pasteur in 1984 in the lab of Jean-Pierre Changeux and was stimulated by discussion with Patrice Boquet, also at Pasteur. On my return to [...]

November 20th, 2016|Blog|Comments Off on The discovery of the molecular mechanism of the neuroparalytic action of tetanus and botulinum neurotoxins

The initial use of Botulinum Toxin at Denmark Hill and Queen Square

The initial use of Botulinum Toxin at Denmark Hill and Queen Square by Prof Philip Thompson ( Adelaide, Australia) In order to understand how Botulinum toxin therapies were introduced it is helpful to go back 30 years to the 1980s. Several things happened at the time.   Prof David Marsden and fellows-Denmark Hill 1984 [...]

November 20th, 2016|Blog|Comments Off on The initial use of Botulinum Toxin at Denmark Hill and Queen Square